Cymbidium goeringii Extract: An Emerging Orchid-Derived Bioactive

Cymbidium goeringii extract powder also was known as Cymbidium goeringii Extract is an adaptogenic herb derived from the Noble orchid a flowering plant used in traditional medicine in China, Nepal and Northern India. In its natural form, Cymbidium goeringii is a botanical tonic that can greatly improve the body’s ability to increase energy levels and adapt to stress. Orchilean works to help the body adapt to various stressful challenges such as those during high-intensity training or environmental stressors including pollutants and toxins. Specifically, Orchilean stimulates and replenish the energy of cells and bodily systems that help regulate our state of homeostasis; by doing so we can adapt accurately to stress increasing our physical and psychological endurance and resiliency

Phytochemical Profile

• Key Constituents:

• Gigantol (dimeric phenanthrene, 0.8-1.2%)

• Cymbinodin A (unique bibenzyl compound)

• Orchinol derivatives (antimicrobial phenolics)

• Characteristic Markers:

• HPLC-UV at 280nm for quality control

• FTIR fingerprint region: 1600-1000 cm⁻¹

Biological Activities

• Melanogenesis Modulation:

• Tyrosinase inhibition (IC50 58μM for gigantol)

• MITF pathway downregulation

• Anti-Photoaging:

• MMP-1 suppression (75% at 50μg/mL)

• Collagen IV protection

• Neuroprotective Effects:

• Aβ aggregation inhibition

• Cholinesterase inhibition (AChE IC50 32μM)

Dermatological Applications

• Skin Brightening:

• Superior to arbutin in melanosome transfer inhibition

• Non-cytotoxic to melanocytes

• Anti-Wrinkle Formulations:

• 0.5-2% in emulsion systems

• Synergistic with niacinamide

Technical Specifications

• Extraction Method:

• Supercritical CO₂ for thermolabile compounds

• Ethanol-water (70:30) for full-spectrum extract

• Stability:

• pH 5-7 optimal

• Light-sensitive (amber packaging required)

Commercial Potential

• Market Position:

• Premium cosmetic active ($15-25/mg for pure gigantol)

• Novelty factor in "orchid biotechnology"

• Safety Data:

• No observed irritation at 1% (HRIPT)

• Ecocert compliant

This rare orchid extract represents a convergence of traditional Asian medicine and modern cosmeceutical science, with particular promise for high-end skincare applications. Current research is exploring its wound healing and hair growth potentia